A while ago I made a post on how you can change the look of RStudio to be custom. File paths have changed since then and so that method is no longer completely valid (though the idea has stayed the same). However, I've just built a package that does all the work for you!
rs.ui takes either a color and generates a theme using color theory or it takes an exact specification of your wanted theme. This way, you can get some ideas and then have the fine control of smaller tweaks. Instead of editing css code, it's a simple, small csv file to edit!
Here's some example themes it has generated: rs.ui can be installed from GitHub with the following command: