My top 10 highlights from this talk: 

1.  If we're all going to eat, someone's got to sell.

2.  You're always selling. And if you don't like to sell, here's my advice: Get over it.

3. Don't play to win —play to win by a landslide.

4. If every time you lost money you just got depressed and angry and you couldn't deal with it, you'd have a very short career.

5. You should absolutely be thinking about which high-risk opportunities you can pursue that you'll have the greatest experience with.

6.  Learn from those who have more years of experience. You have no idea how many hours a day I spent on the phone — like a sponge —learning about finance from those with 15, 20, 25, 30 years of experience. 

7.   Think about what tools you have, that at this moment in time, unlock problems that just simply didn't exist before now. (Great advice) 

8. If you're not passionate about the field you're engaged in you won't have the grit or perseverance to compete with those who are. 

9.  One of my earliest hires was a Russian rocket scientist. And one of my friends from Wall Street called me up

and literally said: "You're not trying to put man on the moon, you're trying to make money." And I said: "I believe that this is the future. The firms that can price derivatives analytically are going to have a real advantage." He was a partner at one of the most successful investment banks that no longer exists. And today, Citadel is one of the largest market makers in the world. 

10.  My biggest stressor is me. I'm always trying to figure out how I can do better. How I can be better. I might be demanding of the people that work for me, but I'm no less demanding of myself.

Listen to #384 Ken Griffin: Founder of Citadel and Citadel Securities on Spotify, Apple Podcasts, or the web.

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